Analysis of Salivary Proteome in Patients with Dental Caries employing Electrophoresis and Mass Spectrometry

Conclusion: New analytical state-of-the-art technologies, such as MS have revolutionized the field of oral biology. These novel technologies open avenues for a comprehensive characterization of the salivary proteins followed by the evaluation of the physiological functions, which could make possible in a near future the development of a new series of synthetic protein for therapeutic propose able to prevent global oral diseases, such as dental caries, one of the most prevalent oral diseases in the world. This approach provides novel insight into profiles of the salivary proteome due to dental decay, which may contribute to improvements in understanding its complex etiology and prevention.